2021 Articles
Volume 3 Issue 4


Psilocybin as an Abortive Treatment for Intractable Migraines: A Case Report

Alicia McCullough, MD.

Volume 3 Issue 4


Over a billion individuals worldwide suffer from an acute migraine attack in a single year. Approximately 1% of these individuals suffer from status migrainosus, which is defined as a migraine that lasts longer than 72 hours. These chronic intractable migraines are often refractory to conventional treatment interventions. In this case report, the use of the psychedelic agent psilocybin is discussed as an alternative treatment modality for chronic intractable migraines. The pathophysiology of migraines is examined, and the literature on psychedelic substances in treating migraines is reviewed.